The treatment of both Crohn’s disease (CD) and ulcerative colitis (UC) has changed over the years. Although corticosteroids are still being used to induce clinical remission in case of severe symptoms, they cannot be maintained due to severe side-effects. Hence, aminosalicylates (UC only) or immunomodulators (thiopurines, methotrexate) are administered during induction and maintenance in the standard step-up approach.